Table 1.
Hormone | Receptor | Functions | References |
---|---|---|---|
Estrogen | Estrogen Receptor-α (ER-α) | To form ligand-ER complex and controlling gene expression. To stimulate proliferation of breast cancer cells |
[7] |
Integrin αvβ3 | NA | [8] | |
DHT | Androgen Receptor (AR) | To form ligand-AR complex and controlling gene expression To stimulate proliferation of prostate cancer cells. |
[9] |
Estrogen Receptor-α (ER-α) | To stimulate proliferation of ER-positive breast cancer cells | [7] | |
Integrin αvβ3 | To stimulate proliferation of ER-negative breast cancer cells | [10] | |
Thyroid hormone | Thyroid hormone Receptor-α (TR-α) | To stimulate cancer cell growth | [11] |
Thyroid hormone Receptor-β (TR-β) | To inhibit cancer cell growth, however, mutant TR-β may activate cancer cell growth | [12] | |
Integrin αvβ3 | To stimulate cancer cell growth | [13] |