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. 2020 Apr 21;21(8):2906. doi: 10.3390/ijms21082906

Table 1.

Hormone receptors and their functions in cancer cells [7,8,9,10,11,12,13].

Hormone Receptor Functions References
Estrogen Estrogen Receptor-α (ER-α) To form ligand-ER complex and controlling gene expression.
To stimulate proliferation of breast cancer cells
[7]
Integrin αvβ3 NA [8]
DHT Androgen Receptor (AR) To form ligand-AR complex and controlling gene expression
To stimulate proliferation of prostate cancer cells.
[9]
Estrogen Receptor-α (ER-α) To stimulate proliferation of ER-positive breast cancer cells [7]
Integrin αvβ3 To stimulate proliferation of ER-negative breast cancer cells [10]
Thyroid hormone Thyroid hormone Receptor-α (TR-α) To stimulate cancer cell growth [11]
Thyroid hormone Receptor-β (TR-β) To inhibit cancer cell growth, however, mutant TR-β may activate cancer cell growth [12]
Integrin αvβ3 To stimulate cancer cell growth [13]