Table 2.

Incidence Rate of CV Events in the Overall Cohort of Prostate Cancer Patients Treated with GnRH Agonists or Antagonists

	GnRH Agonist	GnRH Antagonist	P Value
Patients (n)	9097	530
Patients with CV events (n)	2206	76	<0.001
Overall number of CV events (n)	5478	170
Time to event (mean years ± SD)	1.6 ± 1.3	1.2 ± 1.1
Time to event (median, IQR)	1.3 (1.9)	1.0 (1.5)
Incidence rate/100 person-years	8.80	6.24	0.002

Abbreviations: CV, cardiovascular; GnRH, gonadotropin-releasing hormone; IQR, interquartile; SD, standard deviation.