Table 3.

Incidence of CV Events in the Overall Cohort of Prostate Cancer Patients Treated with GnRH Agonists or Antagonists According to Characteristics at Baseline

	HR	95% CI min	95% CI max	P Value
Age	1.05	1.04	1.06	<0.001
Hypertension	1.57	1.40	1.75	<0.001
Diabetes	1.06	0.97	1.16	0.198
Dyslipidemia	1.63	1.39	1.91	<0.001
Cardiac therapy	1.58	1.42	1.75	<0.001
Previous CV events	3.27	2.75	3.89	<0.001
Treatment
GnRH agonists	1.00
GnRH antagonists	0.76	0.60	0.95	0.018

Abbreviations: CI, confidence interval; CV, cardiovascular; GnRH, gonadotropin-releasing hormone HR, hazard ratio.