Table 5.
Incidence Rate of CV Events in the Sub-Cohort of Prostate Cancer Patients Treated with GnRH Agonists or Antagonist Without Previous CV Events
| GnRH Agonists | GnRH Antagonist | P Value | |
|---|---|---|---|
| Patients (n) | 8300 | 474 | |
| Patients with CV events (n) | 1845 | 60 | <0.001 |
| Overall number of CV events (n) | 4245 | 140 | |
| Time to event (mean years ± SD) | 1.7 ± 1.3 | 1.4 ± 1.1 | |
| Time to event median (IQR) | 1.4 (2.0) | 1.1 (1.5) | |
| Incidence rate/100 person-years | 7.83 | 5.33 | 0.002 |
Abbreviations: CV, cardiovascular; GnRH, gonadotropin-releasing hormone; IQR, interquartile; SD, standard deviation.