Table 1.
Comparison of clinical parameters among people with normal glucose tolerance and prediabetes [±s, n (%)]
| Variable | Polyp-free group with normal glucose tolerance (n = 62) | Polyps group with normal glucose tolerance (n = 46) | Polyp-free group with prediabetes (n = 220) | Polyps group with prediabetes (n = 248) | P-value |
|---|---|---|---|---|---|
| Sex (male/female) | 62 (32/30) | 46 (26/20) | 220 (98/122) | 248 (156/92) f | 0.001 |
| Age (year) | 51.1 ± 11.1 | 54.4 ± 13.2 a | 50.2 ± 10.9 c | 56.3 ± 12.3 ae | 0.008 |
| BMI (kg/m2) | 23.1 ± 2.8 | 23.8 ± 3.1 | 23.7 ± 3.4 | 24.9 ± 3.3 bce | 0.017 |
| WHR | 0.86 ± 0.04 | 0.87 ± 0.05 | 0.88 ± 0.07 | 0.91 ± 0.08 ace | 0.004 |
| SBP (mm Hg) | 121 ± 10 | 124 ± 14 | 124 ± 13 | 122 ± 14 | 0.264 |
| DBP (mm Hg) | 75 ± 13 | 77 ± 12 | 76 ± 12 | 78 ± 10 | 0.318 |
| FPG (mmol/L) | 4.8 ± 0.6 | 4.9 ± 0.5 | 5.8 ± 0.5 ad | 5.9 ± 0.4 ad | 0.029 |
| 2hPG (mmol/L) | 6.7 ± 0.8 | 6.8 ± 0.9 | 8.9 ± 1.1 bd | 9.9 ± 1.0 bde | < 0.001 |
| TG (mmol/L) | 1.32 ± 0.81 | 1.56 ± 0.83 | 1.54 ± 0.91 | 1.69 ± 0.82 ace | 0.037 |
| TCH (mmol/L) | 4.32 ± 0.75 | 4.65 ± 0.72 | 4.98 ± 0.89 | 5.27 ± 0.68 | 0.261 |
| FINS (mIU/L) | 9.31 ± 4.22 | 12.53 ± 5.38 | 11.52 ± 6.27 | 14.71 ± 6.75 a | 0.042 |
| HOMA-IR | 1.98 ± 1.47 | 2.73 ± 1.58 | 2.96 ± 1.15 a | 3.86 ± 1.92 bc | 0.005 |
| Adiponectin (mg/L) | 13.3 ± 3.9 | 9.8 ± 4.8 a | 9.2 ± 4.4 a | 5.6 ± 3.7 bcf | < 0.001 |
| Visfatin (mg/L) | 5.6 ± 3.8 | 8.7 ± 4.8 a | 10.2 ± 5.3 b | 13.9 ± 6.1 bce | 0.007 |
| Leptin (ng/ml) | 16.4 ± 7.2 | 20.5 ± 8.9 | 24.1 ± 9.3 | 28.3 ± 10.2 ac | 0.039 |
| Resistin (ng/ml) | 4.4 ± 0.9 | 5.5 ± 1.1 | 6.1 ± 1.4 a | 7.9 ± 2.1 bc | 0.041 |
| Current smoking (%) | 19 (30.6) | 16 (34.8) | 51 (23.2) | 95 (38.3) f | 0.005 |
| Regular alcohol drinking (%) | 18 (29.0) | 16 (34.9) | 50 (22.7) | 97 (39.1) f | 0.002 |
| Regular exercise (%) | 20 (32.3) | 13 (28.3) | 64 (29.1) | 53 (21.4) | 0.156 |
| Regular vegetables consumption (%) | 24 (38.7) | 12 (26.1) | 68 (30.9) | 69 (27.8) | 0.359 |
| Family history of colon cancer (%) | 2 (3.2) | 6 (8.7) a | 13 (5.9) | 25 (10.1) be | 0.005 |
Data are presented mean ± standard deviations or numbers (%); Differences among four groups analyzed using one-way analysis of variance or x2 test, and least-significant difference (LSD) analysis was used for comparison between the two groups. Versus polyp-free group with normal glucose tolerance, a = P < 0.05, b = P < 0.01; versus polyps group with normal glucose tolerance, c = P < 0.05, d = P < 0.01;versus polyp-free group with prediabetes, e = P < 0.05, f = P < 0.01