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Immune cell alteration before Y90, after Y90, and after D + T. Patient peripheral blood mononuclear cells were analyzed by flow cytometry. Representative plots show cell population gates for CD8+ T cells, CD4+ T cells, PD‐1+ CD8+ T cells, PD‐1+ CD4+ T cells, MDSCs, regulatory T cells, B cells, and NK cells.
Abbreviations: D + T, durvalumab and tremelimumab; MDSC, myeloid‐derived suppressive cell; NK, natural killer; Treg, regulatory T cell; Y90, yttrium‐90.
