Table 3.
Preoperative characteristics in patients with EuroSCORE II ≥ 4.15
| Variables | EuroSCORE II≥ 4.15 (n = 101) | Glutamate (n = 56) |
Control (n = 45) |
p-value |
|---|---|---|---|---|
| Age (years) | 76 [71–79] | 76 [70–79] | 76 [72–79] | 0.85 |
| Female gender | 38% (38) | 32% (18) | 44% (20) | 0.22 |
| BMI (kg•m2) | 25 [22–28] | 25 [22–28] | 26 [23–28] | 0.64 |
| EuroSCORE II | 5.83 [4.89–7.85] | 5.86 [5.00–7.54] | 5.83 [4.54–8.97] | 0.82 |
| Diabetes | 29% (29) | 27% (14) | 33% (15) | 0.38 |
| Hypertension | 72% (72) | 68% (38) | 76% (34) | 0.50 |
| COPD | 18% (18) | 21% (12) | 13% (6) | 0.31 |
| NT-proBNP (ng•L−1) | 1010 [450–2345] | 790 [425–1895] | 1265 [465–2915] | 0.15 |
| Hemoglobin (g•L−1) | 132 [121–142] | 133 [125–143] | 130 [115–139] | 0.08 |
| Troponin T (ng•L−1) | 10 [0–90] | 0 [0–30] | 40 [0–390] | < 0.0001 |
| p-Creatinine (μmol•L−1) | 97 [88–122] | 97 [87–115] | 97 [90–123] | 0.51 |
| eGFR (mL•min−1•1.73 m−2) | 50 [41––68] | 50 [44–72] | 51 [38–66] | 0.38 |
| Cerebrovascular disease | 21% (21) | 20% (11) | 23% (10) | 0.81 |
| Three-vessel disease | 83% (83) | 82% (46) | 82% (37) | 1 |
| Left main stenosis | 48% (48) | 45% (25) | 51% (23) | 0.55 |
| AMI < 3 weeks | 73% (73) | 73% (41) | 71% (32) | 0.83 |
| History of AMI | 82% (82) | 82% (46) | 80% (36) | 0.80 |
| CCS IV | 80% (80) | 82% (46) | 76% (34) | 0.47 |
| Angina at rest < 48 h preoperatively | 23% (23) | 13% (7) | 36% (16) | 0.007 |
| Moderate LV dysfunction | 21% (21) | 23% (13) | 18% (8) | 0.62 |
| Severe LV dysfunction | 14% (14) | 9% (5) | 20% (9) | 0.15 |
Data given as medians [interquartile range] or percentages (number)
AMI < 3 weeks: acute myocardial infarction within 3 weeks of surgery; Angina at rest < 48 h preoperatively: angina at rest within 48 h before surgery
BMI body mass index, CCS: Canadian Cardiovascular Society, COPD chronic obstructive pulmonary disease, EuroSCORE II European system for cardiac operative risk evaluation II, LV left ventricular eGFR: estimated glomerular filtration rate according to MDRD formula