Table 4.
Intraoperative and postoperative characteristics in patients with EuroSCORE II ≥ 4.15
| Variables | EuroSCOREII ≥ 4.15 (n = 101) |
Glutamate (n = 56) |
Control (n = 45) |
p-value |
|---|---|---|---|---|
| Aortic crossclamp time (min) | 53 [42–67] | 54 [41–65] | 52 [42–67] | 0.91 |
| CPB time (min) | 80 [65–106] | 81 [64–104] | 79 [67–107] | 0.74 |
| Reperfusion time (min) | 23 [16–30] | 24 [17–30] | 21 [16–29] | 0.53 |
| NT-proBNP POD1 (ng•L−1) | 4170 [2850–6185] | 3786 [2630–5380] | 4675 [3010–6650] | 0.21 |
| NT-proBNP POD3 (ng•L−1) | 6650 [3800–9970] | 4845 [3426–7423] | 8430 [5370–14,100] | 0.001 |
| Delta NT-proBNP POD1-Pre (ng•L−1) | 2800 [1650–4760] | 2653 [1540–3675] | 3050 [2030–5560] | 0.13 |
| Delta NT-proBNP POD3-Pre (ng•L−1) | 5210 [3115–8595] | 3900 [2995–6260] | 6745 [3455–12,687] | 0.012 |
| CK-MB POD1 (µg•L−1) | 18 [11–25] | 14 [9–23] | 19 [12–26] | 0.12 |
| TroponinT POD3 (ng•L−1) | 390 [190–730] | 290 [160–480] | 550 [210–860] | 0.015 |
| Delta Troponin T POD3-Pre (ng•L−1) | 270 [135–600] | 270 [130–450] | 350 [150–680] | 0.44 |
| Inotropic support | 43% (43) | 43% (24) | 42% (19) | 1.00 |
| ICU stay (h) | 22 [19–42] | 21 [19–26] | 25 [22–45] | 0.022 |
| ICU stay > 72 h | 18% (18) | 16% (9) | 20% (9) | 0.61 |
| Ventilation time (h) | 5 [3–12] | 4 [3–9] | 5 [3–20] | 0.3 |
| Ventilation time > 48 h | 11% (11) | 11% (6) | 11% (5) | 1 |
| PHF | 22% (22) | 15% (8) | 31% (14) | 0.053 |
| Severe PHF | 9% (9) | 4% (2) | 16% (7) | 0.074 |
| Postoperative stroke | 4% (3) | 4% (2) | 4% (2) | 1 |
| AKI | 29% (29) | 25% (14) | 33% (15) | 0.51 |
| Hospital Mortality | 5% (5) | 4% (2) | 7% (3) | 0.65 |
Data given as medians [interquartile range] or percentages (number)
AKI acute kidney injury, CK-MB creatine kinase-MB isoenzyme, CPB cardiopulmonary bypass, ICU intensive care unit, PHF postoperative heart failure, POD postoperative day