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. 2020 Apr 28;11:517. doi: 10.3389/fmicb.2020.00517

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Copyright © 2020 Balzano, Sardo, Blasio, Chahine, Dell’Anno, Sansone and Brunet.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Current knowledge about metallothioneins and phytochelatins. (A,B) Taxonomic origin of the GenBank proteins annotated as metallothionein (MT), glutamate–cysteine ligase (GCL), glutathione synthase (GSH), and phytochelatin synthase (PCS) for (A) all eukaryotic organisms and (B) within eukaryotic microalgae. Please note the different scale on the y-axis (C,D) number of papers, as reported by Web of Sciences (September 2019), containing the keywords (C) “metallothionein*” and (D) “phytochelatin*” alone or in association with the keywords “microalga*/phytoplankt*/phytobenth*.” Keyword searches were case insensitive.