Table 2.
Comparison of echocardiographic parameters across different subgroups
| Variables | HP N = 18 | Control A N = 18 | PHP N = 8 | Control B N = 8 | Pa value | Pb value | Pc value | Pc,d | Pc,e | Pc,f |
|---|---|---|---|---|---|---|---|---|---|---|
| Age of evaluation (y) | 45.4 ± 15.4 | 45.9 ± 14.8 | 20.6 ± 5.3 | 22.6 ± 6.4 | 0.501 | 0.120 | 0.000 | – | – | – |
| BMI (kg/m2) | 25.1 ± 3.9 | 23.0 ± 2.1 | 22.6 ± 3.3 | 18.6 ± 3.9 | 0.050 | 0.004 | 0.074 | – | – | – |
| HR (beats/min) | 73.6 ± 9.9 | 69.4 ± 10.6 | 70.0 ± 4.6 | 72.3 ± 5.6 | 0.269 | 0.417 | 0.404 | – | – | – |
| Adjusted for age at evaluation and BMI | ||||||||||
| IVSd (mm) | 7.6 ± 1.1 | 7.8 ± 1.9 | 6.4 ± 0.6 | 7.1 ± 1.6 | 0.600 | 0.153 | 0.009 | 0.141 | 0.159 | 0.173 |
| LVPWd (mm) | 7.7 ± 1.0 | 7.8 ± 1.6 | 6.4 ± 0.6 | 6.5 ± 1.4 | 0.452 | 0.336 | 0.005 | 0.186 | 0.247 | 0.237 |
| LVEDD (mm) | 46.9 ± 5.1 | 46.6 ± 3.9 | 45.1 ± 5.0 | 42.9 ± 4.5 | 0.732 | 0.836 | 0.398 | 0.124 | 0.130 | 0.141 |
| LVEF (%) | 68.4 ± 6.4 | 70.8 ± 6.1 | 66.5 ± 7.4 | 70.4 ± 7.1 | 0.275 | 0.314 | 0.422 | 0.763 | 0.939 | 0.855 |
| LVM (g) | 117.9 ± 32.1 | 120.2 ± 43.9 | 86.2 ± 20.3 | 87.5 ± 26.6 | 0.517 | 0.288 | 0.020 | 0.783 | 0.888 | 0.818 |
| LVMI (g/m2) | 69.2 ± 16.0 | 71.4 ± 27.0 | 54.6 ± 6.4 | 51.3 ± 12.2 | 0.644 | 0.824 | 0.050 | 0.923 | 0.943 | 0.863 |
| RWT | 0.33 ± 0.04 | 0.34 ± 0.07 | 0.28 ± 0.04 | 0.31 ± 0.07 | 0.557 | 0.369 | 0.022 | 0.023 | 0.032 | 0.039 |
| E/A ratio | 0.9 ± 0.2 | NA | 1.4 ± 0.1 | NA | – | – | 0.000 | 0.043 | 0.024 | 0.036 |
Date represent the means (SD)
a: comparison between HP and control A, adjusted for BMI
b: comparison between PHP and control B, adjusted for BMI
c: comparison between HP and PHP
d: P value adjusted for gender, age at evaluation, and BMI
e: P value adjusted for gender, age at evaluation, BMI and serum calcium
f: P value adjusted for gender, age at evaluation, BMI, and serum phosphorus
Abbreviations: HP hypoparathyroidism; PHP pseudohypoparathyroidism; BMI body mass index; HR heart rate; IVSd interventricular septum end-diastolic thickness; LVPWd left ventricular posterior wall end-diastolic thickness; LVEDD left ventricular end-diastolic diameter; LVEF left ventricular ejection fraction; LVM left ventricular mass; LVMI left ventricular mass index; RWT relative wall thickness; E early diastolic mitral inflow velocity; A: late diastolic mitral inflow velocity