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. 2020 May 11;12:64. doi: 10.1186/s13148-020-00857-x

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Properties of hyper- and hypomethylated domains in pig and cow. a Stacked bar chart of the percentage genome coverage of hypermethylated domains (HyperDomains; ≥ 75% methylation) and hypomethylated (HypoDomains; ≤ 25%) in oocytes from pig, cow, mouse and human. b Correlation between gene body methylation and gene expression in pig and cow oocytes. c Violin plots showing distribution of DNA methylation values (%) of oocyte HyperDomains and HypoDomains across the indicated stages in pig (c) and cow (d). The data in c are based on 55380 HyperDomains and 54959 HypoDomains and in d on 40453 HyperDomains and 57969 HypoDomains