FIGURE 4.

Serum levels of IL17A, IL17C, CXCL9, and TGF-α patients with UC. Protein expression in serum was analyzed by proximity extension assay and is presented in arbitrary unit NPX. Serum protein levels of IL17A (A), IL17C (B), CXCL9 (C), and TGF-α (D) in patients with UC with moderate/severe disease (Mayo score ≥6, n = 22), mild disease (Mayo score 3–5, n = 18), complete remission with IBS-like symptoms (n = 19), complete remission without IBS-like symptoms (n = 44), and healthy subjects (n = 19). Statistical difference between groups was assessed by the Kruskal-Wallis test followed by Dunn’s multiple comparisons test; only significant differences are shown: *P < 0.05; ^**P < 0.01; ^***P < 0.001; ^****P < 0.0001. Each symbol represents 1 individual, and horizontal lines indicate the median of the group.