TABLE 5.

Increase in MS risk caused by increase of 1 and 2 SD of gene expression mean.

Effect	Gene	Tissue	Gene expression mean	Gene expression level after increase by 1 SD	Increase in risk	Gene expression level after increase by 2 SD	Increase in risk
Total	CCL2	MEDU	6.40	7.44	31%	8.64	62%
Direct	CCL2	MEDU	6.40	7.44	50%	8.64	100%
Total	NFKB1	CRBL	6.09	6.34	39%	6.60	78%
Direct	NFKB1	CRBL	6.09	6.34	111%	6.60	222%
Direct	CCL2	CRBL	4.50	5.00	−41%	5.56	−82%
Direct	TNFRSF1A	CRBL	5.42	5.72	44%	6.05	88%