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. 2020 May 5;11:441. doi: 10.3389/fgene.2020.00441

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Copyright © 2020 Zhang, Wang, Chen, Guo and Hong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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External validation of a prognostic stemness index-related gene signature for primary low-grade glioma (LGG). (A) Kaplan-Meier analysis of OS for low-risk and high-risk patients in the external validation cohort. Additionally, the table indicating the number at risk for each group at corresponding time points. (B) The time-dependent receiver operating characteristics (ROC) curve for 1-, 3-, and 5-years OS predictions for the nomogram compared with actual observations. (C) The heatmap shows the expression of the seven genes between two risk groups in the CGGA cohort. (D) Time-dependent ROC for 3- and 5-years OS predictions for the nomogram compared with actual observations. Calibration plot of nomogram for predicting probabilities of 3- (E) and 5-year (F) OS of primary LGG patients in the CGGA database.