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. 2020 May 5;11:441. doi: 10.3389/fgene.2020.00441

TABLE 3.

Comprehensive comparison of the accuracy and discrimination in five models.

Index Model 1 vs. Model 2 Model 1 vs. Model 3 Model 1 vs. Model 4 Model 1 vs. Model 5 Model4 vs. Model 5
IDI (1 year) −0.037 (p = 0.274) −0.063 (p = 0.02) 0.084 (p = 0.002) 0.108 (p < 0.001) 0.025 (p = 0.186)
Continuous NRI (1 year) −0.598 (p = 0.010) −0.663 (p < 0.001) 0.458 (p = 0.016) 0.708 (p < 0.001) 0.422 (p = 0.032)
IDI (3 year) −0.146 (p = 0.040) −0.178 (p = 0.006) 0.165 (p = 0.014) 0.214 (p < 0.001) 0.049 (p = 0.102)
Continuous NRI (3 year) −0.548 (p = 0.022) −0.508 (p < 0.001) 0.317 (p = 0.028) 0.433 (p < 0.001) 0.508 (p = 0.032)
IDI (5 year) −0.189 (p = 0.044) −0.211 (p = 0.056) 0.122 (p = 0.158) 0.177 (p = 0.018) 0.055 (p = 0.292)
Continuous NRI (5 year) −0.530 (p = 0.078) −0.366 (p = 0.058) 0.157 (p = 0.274) 0.410 (p = 0.036) 0.398 (p = 0.106)

Model 1: only the SI−risk signature was enrolled in the prognostic factor; Model 2: mRNAsi was enrolled in the prognostic factor; Model 3: corrected mRNAsi was enrolled in the prognostic factor; Model 4: age, gender, grade, radiation therapy, chemotherapy, and IDH status were enrolled in the prognostic factors; Model 5: age, gender, grade, radiation therapy, chemotherapy, IDH status, and risk group were enrolled in the prognostic factors. NRI, net reclassification improvement; IDI, integrated discrimination improvement.