TABLE 3.
Index | Model 1 vs. Model 2 | Model 1 vs. Model 3 | Model 1 vs. Model 4 | Model 1 vs. Model 5 | Model4 vs. Model 5 |
IDI (1 year) | −0.037 (p = 0.274) | −0.063 (p = 0.02) | 0.084 (p = 0.002) | 0.108 (p < 0.001) | 0.025 (p = 0.186) |
Continuous NRI (1 year) | −0.598 (p = 0.010) | −0.663 (p < 0.001) | 0.458 (p = 0.016) | 0.708 (p < 0.001) | 0.422 (p = 0.032) |
IDI (3 year) | −0.146 (p = 0.040) | −0.178 (p = 0.006) | 0.165 (p = 0.014) | 0.214 (p < 0.001) | 0.049 (p = 0.102) |
Continuous NRI (3 year) | −0.548 (p = 0.022) | −0.508 (p < 0.001) | 0.317 (p = 0.028) | 0.433 (p < 0.001) | 0.508 (p = 0.032) |
IDI (5 year) | −0.189 (p = 0.044) | −0.211 (p = 0.056) | 0.122 (p = 0.158) | 0.177 (p = 0.018) | 0.055 (p = 0.292) |
Continuous NRI (5 year) | −0.530 (p = 0.078) | −0.366 (p = 0.058) | 0.157 (p = 0.274) | 0.410 (p = 0.036) | 0.398 (p = 0.106) |
Model 1: only the SI−risk signature was enrolled in the prognostic factor; Model 2: mRNAsi was enrolled in the prognostic factor; Model 3: corrected mRNAsi was enrolled in the prognostic factor; Model 4: age, gender, grade, radiation therapy, chemotherapy, and IDH status were enrolled in the prognostic factors; Model 5: age, gender, grade, radiation therapy, chemotherapy, IDH status, and risk group were enrolled in the prognostic factors. NRI, net reclassification improvement; IDI, integrated discrimination improvement.