Table 3.

Comparison of the number of channel types determined from single channel measurements and calculation

RyR expression vector ratio	RyR1 channel types
WT:ΔFF	WT	Heterotetrameric	ΔFF
3:1	5 (4.1)	7 (8.8)	1 (0.1)
1:1	1 (0.8)	12 (11.4)	0 (0.8)
1:3	0 (0.1)	3 (2.0)	0 (0.9)

Number of experimentally determined homotetrameric WT (Group 1, Table 2) heterotetrameric (Groups 2–4) and homotetrameric ΔFF (Group 5) channels at the indicated expression vector ratios using 7 μg total DNA/dish. In parentheses are the number of predicted channel types assuming uniform distribution of WT and ΔFF subunits in channel complexes.