Table 1.
Characteristics | Case no. | (%) |
---|---|---|
Age (y) | ||
Mean (SD): 71.2 (4.9) | ||
Median (range): 71.0 (65‐83) | ||
Body mass index (kg/m2)a | ||
Mean (SD): 24.4 (3.2) | ||
Gender | ||
Female | 16 | 23.2 |
Male | 53 | 76.8 |
History of head and neck cancer | ||
No | 49 | 71.0 |
Yes | 20 | 29.0 |
History of radiation therapy | ||
No | 58 | 84.1 |
Yes | 11 | 15.9 |
Cigarette smoking | ||
No | 28 | 40.6 |
Ex‐smoker | 22 | 31.9 |
Yes | 19 | 27.5 |
Alcohol drinking | ||
No | 53 | 76.8 |
Ex‐drinker | 10 | 14.5 |
Yes | 6 | 8.7 |
Betel quid chewing | ||
No | 51 | 73.9 |
Ex‐chewer | 18 | 26.1 |
Yes | 0 | 0.0 |
Candida infection | ||
No | 62 | 89.9 |
Yes | 7 | 10.1 |
Diabetes mellitus | ||
No | 52 | 75.4 |
Yes | 17 | 24.6 |
Metformin taken | ||
No | 58 | 84.1 |
Yes | 11 | 15.9 |
Multi‐focus sites | ||
No | 56 | 81.2 |
Yes | 13 | 18.8 |
Location of leukoplakiab | ||
Buccal | 54 | 64.3 |
Tongue | 12 | 14.3 |
Gum | 5 | 6.0 |
Labial | 4 | 4.8 |
Mouth floor | 1 | 1.2 |
Hard palate | 1 | 1.2 |
Retromolar | 7 | 8.3 |
Morphologyb | ||
Homogeneous | 42 | 50.0 |
Nonhomogeneous | 42 | 50.0 |
Pathology | ||
Squamous hyperplasia | 15 | 21.7 |
Mild dysplasia | 34 | 49.3 |
Moderate dysplasia | 12 | 17.4 |
Severe dysplasia/carcinoma in situ | 8 | 11.6 |
Postoperative recurrence | ||
No | 46 | 66.7 |
Yes | 23 | 33.3 |
Follow‐up duration (mo) | ||
Mean (SD): 42.5 (35.2) | ||
Median (range): 29.0 (3.2‐145.1) | ||
Total area of leukoplakia (cm2) | ||
Mean (SD): 2.3 (1.9) | ||
Median (range): 1.8 (0.1‐10.6) | ||
Malignant transformation | ||
No | 61 | 88.4 |
Yes | 8 | 11.6 |
One missing data in body mass index (n = 68).
Thirteen out of 69 patients had multiple sites of oral leukoplakia, so the number of total lesions was 84.