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. 2020 Jan 13;42(5):1014–1023. doi: 10.1002/hed.26074

Table 1.

Clincopathological characteristics of elderly patients with oral cavity leukoplakia (n = 69)

Characteristics Case no. (%)
Age (y)
Mean (SD): 71.2 (4.9)
Median (range): 71.0 (65‐83)
Body mass index (kg/m2)a
Mean (SD): 24.4 (3.2)
Gender
Female 16 23.2
Male 53 76.8
History of head and neck cancer
No 49 71.0
Yes 20 29.0
History of radiation therapy
No 58 84.1
Yes 11 15.9
Cigarette smoking
No 28 40.6
Ex‐smoker 22 31.9
Yes 19 27.5
Alcohol drinking
No 53 76.8
Ex‐drinker 10 14.5
Yes 6 8.7
Betel quid chewing
No 51 73.9
Ex‐chewer 18 26.1
Yes 0 0.0
Candida infection
No 62 89.9
Yes 7 10.1
Diabetes mellitus
No 52 75.4
Yes 17 24.6
Metformin taken
No 58 84.1
Yes 11 15.9
Multi‐focus sites
No 56 81.2
Yes 13 18.8
Location of leukoplakiab
Buccal 54 64.3
Tongue 12 14.3
Gum 5 6.0
Labial 4 4.8
Mouth floor 1 1.2
Hard palate 1 1.2
Retromolar 7 8.3
Morphologyb
Homogeneous 42 50.0
Nonhomogeneous 42 50.0
Pathology
Squamous hyperplasia 15 21.7
Mild dysplasia 34 49.3
Moderate dysplasia 12 17.4
Severe dysplasia/carcinoma in situ 8 11.6
Postoperative recurrence
No 46 66.7
Yes 23 33.3
Follow‐up duration (mo)
Mean (SD): 42.5 (35.2)
Median (range): 29.0 (3.2‐145.1)
Total area of leukoplakia (cm2)
Mean (SD): 2.3 (1.9)
Median (range): 1.8 (0.1‐10.6)
Malignant transformation
No 61 88.4
Yes 8 11.6
a

One missing data in body mass index (n = 68).

b

Thirteen out of 69 patients had multiple sites of oral leukoplakia, so the number of total lesions was 84.