Table 3.
Risk of post‐9/11 systemic autoimmune disease among responders enrolled in the WTC Health Registrya
| Model 1 | Model 2 | Model 3 | Model 4 | |
|---|---|---|---|---|
| adjusted RR (95% CI) | adjusted RR (95% CI) | adjusted RR (95% CI) | adjusted RR (95% CI) | |
| 9/11‐related exposure | ||||
| Dust intensity | – | – | – | – |
| Intense | 1.86 (1.02–3.40)b | – | – | – |
| None/some | Referent | – | – | – |
| Dust composite score | ||||
| High | – | 1.86 (0.98–3.53) | – | – |
| Low | – | Referent | – | – |
| Months worked at WTC site (continuous) | – | – | 1.10 (0.97–1.24) | – |
| PTSD | ||||
| Yes | – | – | – | 1.42 (0.72–2.80) |
| No | – | – | – | Referent |
| Demographics | ||||
| Age at wave 3 (continuous) | 1.03 (1.01–1.06)b | 1.04 (1.01–1.06)b | 1.04 (1.01–1.06)b | 1.03 (1.01–1.06)b |
| Sex | ||||
| Female | 3.96 (2.34–6.70)b | 4.10 (2.39–7.06)b | 3.41 (2.04–5.73)b | 3.75 (2.25–6.25)b |
| Male | Referent | Referent | Referent | Referent |
| Race/ethnicity | ||||
| Non‐Latino white | Referent | Referent | Referent | Referent |
| Non‐Latino African American | 1.24 (0.49–3.13) | 1.70 (0.77–3.79) | 1.39 (0.59–3.29) | 1.39 (0.62–3.12) |
| Latino | 1.39 (0.65–2.99) | 1.37 (0.64–2.93) | 1.31 (0.61–2.83) | 1.07 (0.49–2.33) |
| Asian and other | 0.70 (0.17–2.91) | 0.68 (0.17–2.82) | 0.68 (0.17–2.82) | 0.70 (0.17–2.90) |
| Educational attainment | ||||
| High school or less | – | – | – | 2.21 (1.16–4.21)b |
| Some college | – | – | – | 1.91 (1.03–3.56)b |
| College graduate and higher | – | – | – | Referent |
| Smoking history | ||||
| Ever | 1.01 (0.59–1.70) | 1.03 (0.62–1.71) | 0.98 (0.59–1.65) | 0.98 (0.59–1.63) |
| Never | Referent | Referent | Referent | Referent |
a
WTC = World Trade Center; RR = risk ratio; 95% CI = 95% confidence interval; PTSD = posttraumatic stress disorder.
b
P < 0.05.