Table 2.

Preoperative and postoperative visual, refractive, topographic and tomographic data analysis in the standard epithelium‐off cross‐linking (SCXL) group

Variable	Preoperative Mean ± SD	Postoperative 6th month Mean ± SD	Postoperative 12th month Mean ± SD	Postoperative 24th month Mean ± SD	Difference (post–pre) Mean ± SD (95% CI)
Visual outcomes
UDVA	1.11 ± 0.43	0.97 ± 0.8	0.93 ± 0.35	0.85 ± 0.34	−0.26 ± 0.12 (−0.30: −0.21)
P1 < 0.0001, P2 < 0.0001, P3 < 0.0001, P4 = 0.047, P5 < 0.0001, P6 < 0.0001
CDVA	0.47 ± 0.40	0.40 ± 0.37	0.27 ± 0.29	0.23 ± 0.25	−0.24 ± 0.18 (−0.32: −0.18)
P1 < 0.0001, P2 < 0.0001, P3 < 0.0001, P4 < 0.0001, P5 < 0.0001, P6 = 0.001
Refractive outcomes
Sphere	−3.88 ± 2.65	−3.51 ± 2.53	−3.28 ± 2.45	−2.79 ± 2.12	1.09 ± 1.11 (0.67:1.49)
P1 < 0.0001, P2 < 0.0001, P3 < 0.0001, P4 = 0.002, P5 = 0.005, P6 = 0.06
Cylinder	−3.32 ± 1.37	−3.25 ± 1.36	−3.11 ± 1.42	−3.01 ± 1.40	0.31 ± 0.19 (0.24:0.38)
P1 = 0.08, P2 < 0.0001, P3 < 0.0001, P4 = 0.03, P5 < 0.0001, P6 = 0.02
SE	−5.53 ± 2.99	−5.13 ± 2.85	−4.84 ± 2.80	−4.30 ± 2.50	1.23 ± 1.12 (0.82:1.65)
P1 < 0.0001, P2 < 0.0001, P3 < 0.0001, P4 < 0.0001, P5 = 0.001, P6 = 0.04
Topographic outcomes:
Kmax	50.78 ± 3.82	50.35 ± 3.70	50.18 ± 3.62	49.61 ± 3.67	−1.17 ± 1.01 (−1.54: −0.79)
P1 = 0.003, P2 < 0.0001, P3 < 0.0001, P4 = 0.04, P5 < 0.0001, P6 < 0.0001
Pachymetry	453.07 ± 30.55	449.53 ± 30.79	448.47 ± 30.56	444.17 ± 33.25	−8.9 ± 14.95 (−14.48: −3.32)
P1 < 0.0001, P2 = 0.04, P3 = 0.003, P4 = 1.00, P5 = 1.00, P6 = 1.00

P1 compared pre and post 6 ms, P2 compared pre and post 12 ms, P3 compared pre and post 24 ms, P4 compared. post 6 ms and post 12 ms, P5 compared post 6 ms and post 24 ms, P6 compared post 12 ms and post 24 ms, and CI is confidence of interval