Table 3.

Preoperative and postoperative visual, refractive, topographic and tomographic data analysis in the accelerated epithelium‐off cross‐linking (ACXL) group

Variable	Preoperative Mean ± SD	Postoperative 6th month Mean ± SD	Postoperative 12th month Mean ± SD	Postoperative 24th month Mean ± SD	Difference (post–pre) Mean ± SD (95% CI)
Visual outcomes:
UDVA	0.97 ± 0.26	0.88 ± 0.24	0.81 ± 0.25	0.93 ± 0.28	−0.04 ± 0.22 (−0.11:0.06)
P1 = 0.01, P2 = 0.007, P3 = 0.48, P4 = 0.02, P5 = .04, P6 = 0.009
CDVA	0.41 ± 0.20	0.35 ± 0.19	0.30 ± 0.21	0.38 ± 0.28	−0.03 ± 0.21 (−0.08:0.08)
P1 = 0.03, P2 = 0.01, P3 = 0.09, P4 = 0.03, P5 = 0.54, P6 = 0.01
Refractive outcomes:
Sphere	−3.46 ± 2.28	−3.21 ± 2.29	−2.97 ± 2.36	−3.26 ± 2.63	0.20 ± 0.74 (−0.21:0.38)
P1 = 0.04, P2 = 0.01, P3 = 0.40, P4 = 0.03, P5 = 1.00, P6 = 0.04
Cylinder	−3.53 ± 1.15	−3.44 ± 1.14	−3.32 ± 1.18	−3.52 ± 1.24	0.01 ± 0.45 (−0.17:0.20)
P1 = 0.52 P2 = 0.09, P3 = 1.00, P4 = 1.00, P5 = 1.00, P6 = 0.86
SE	−5.23 ± 2.24	−4.93 ± 2.25	−4.67 ± 2.32	−5.03 ± 2.64	0.20 ± 0.92 (−0.25:0.45)
P1 = 0.03, P2 = 0.01, P3 = 0.82, P4 = 0.04, P5 = 1.00, P6 = 0.06
Topographic outcomes:
Kmax	50.70 ± 3.51	50.38 ± 3.49	50.12 ± 3.53	50.47 ± 3.72	−0.23 ± 1.17 (−0.60:0.72)
P1 = 0.03, P2 = 0.01, P3 = 1.00, P4 = 0.02, P5 = 0.85, P6 = 1.00
Pachymetry	453.47 ± 41.67	452.33 ± 41.45	449.97 ± 41.54	449.76 ± 45.80	−3.71 ± 7.76 (−12.24:4.79)
P1 = 0.74, P2 = 0.01, P3 = 1.00, P4 = 0.08, P5 = 0.04, P6 = 1.00

P1 compared pre and post 6 ms, P2 compared pre and post 12 ms, P3 compared pre and post 24 ms, P4 compared post 6 ms and post 12 ms, P5 compared post 6 ms and post 24 ms, P6 compared post 12 ms and post 24 ms, and CI is confidence of interval