Table 2.
Predisposing risk factors, prevalence of previous antibiotic treatment prior to culture and corneal culture outcome in patients with infectious keratitis
| Total | CLW | No known | OSD | OT | Corneal transplant | Eyelid disorder | Blind/severely diseased eye | Other ocular surgery | |
|---|---|---|---|---|---|---|---|---|---|
| Total | 398 | 181 | 76 | 43 | 32 | 28 | 22 | 9 | 7 |
|
Culture positive (% of total in group) (No prior antibiotic/prior antibiotic) |
285* (72%) (236/48) |
127* (70%) (113/13) |
54 (71%) (46/8) |
29 (67%) (24/5) |
22 (69%) (13/9) |
25 (89%) (21/4) |
17 (77%) (12/5) |
7 (78%) (5/2) |
4 (57%) (2/2) |
| Polymicrobial growth [% of culture positive in group] | 77* [27%] | 26* [20%] | 21 [39%] | 6 [21%] | 6 [27%] | 10 [40%] | 7 [41%] | 1 [14%] | 0 [0%] |
|
Culture negative (% of total in group) (No prior antibiotic/prior antibiotic) |
113 (28%) (86/27) |
54 (30%) (49/5) |
22 (29%) (19/3) |
14 (33%) (9/5) |
10 (31%) (6/4) |
3 (11%) (1/2) |
5 (23%) (1/4) |
2 (22%) (0/2) |
3 (43%) (1/2) |
Corneal transplant: Penetrating keratoplasty, DSAEK, Superficial lamellar keratoplasty. Eyelid disorder: closure defect, trachoma, entropion, ectropion. Percentages within parentheses () refer to the proportions of culture positive and culture negative cases, respectively, in the respective risk factor group. Percentages within square brackets [] refer to the proportion of polymicrobial growth, in the respective risk factor groups of positive corneal culture cases.
CLW = contact lens wear; OSD = ocular surface disease; OT = ocular trauma.
* For one patient, it was unknown whether antibiotic treatment had been initiated prior to sampling.