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. 2019 Dec 16;146(12):3485–3494. doi: 10.1002/ijc.32815

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© 2019 The Authors. International Journal of Cancer published by John Wiley & Sons Ltd on behalf of UICC

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Ubiquity of C‐ETACs. (a) C‐ETACs were evaluated in 5,509 previously diagnosed cases of cancers. Dark bars represent percentage of total samples in each cancer type (and overall) where C‐ETACs could be detected. (b) C‐ETACs were detected with comparable frequency in metastatic (M) as well as nonmetastatic (NM) cancer samples (UA: metastatic status unavailable). (c) C‐ETACs detection was irrespective of treatment and radiological status. T, N: treated with presently no radiological evidence of disease; T, P: treated with radiologically evident disease; N, P: therapy naïve with radiologically evident disease. (d) C‐ETAC counts in presurgery (dark bar) and postsurgery (light bar) sample.