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. 2020 Mar 17;72(5):714–725. doi: 10.1002/art.41184

Figure 4.

Figure 4

B cell–rich synovitis at different rheumatoid arthritis (RA) disease stages. A, Prevalence of B cell–rich synovitis in the cohort of patients with early RA and in the cohort of patients with established RA with an inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). B–D, Krenn synovitis score (B), C‐reactive protein (CRP) level (C), and Disease Activity Score in 28 joints (DAS28) using the erythrocyte sedimentation rate (D) in B cell–poor and B cell–rich patients in the early RA cohort and the TNFi‐IR cohort. Symbols represent individual patients (n = 143 for early RA and 155 for TNFi‐IR); horizontal lines and error bars show the median and interquartile range in B and the mean ± SD in C and D. * = P < 0.05 by chi‐square test in A; by Mann‐Whitney test in B–D. NS = not significant.