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Effect of SP‐11 on intestinal hyperpermeability induced by stress. Partial restraint stress (PRS) increased intestinal FITC‐dextran permeability in comparison with non‐stressed animals treated with saline (saline group: n = 8 and saline + PRS group: n = 9, *P < .05). SP‐11 treatment showed a trend toward reduced gut hyperpermeability of stressed animals (SP‐11 + saline group: n = 8, P = .07)
