Figure 1.

A 6068 bp chromosomal deletion prevents infection of S. islandicus by SSV9. (a) Gene cluster of the parental ΔA1 genome and the deleted or disrupted genes of the evolved resistant strain represented with a blue line. The arCOG predicted functions for the genes are color coded. (b) Host growth (OD₆₀₀), (c) PFU/ml and (d) SSV9 genomes/ml over the course of SSV9 infection in ∆A1 (orange) and ∆A1∆6068 (blue). The strains challenged with SSV9 are represented in solid lines and the control lines are dashed. In c and d, SSV9 decay over the course of infection is represented (solid black)