Figure 4: MERS-CoV antibody kinetics.

The left panel shows data for studies reporting IgG concentration in units of optical density, while the right panel shows data for studies reporting neutralizing antibodies in units of titers. The plotting symbols indicate whether a measurement was above the cutoff for the assay being used, if reported in the study. Some studies reported titers that were lower than or greater than some threshold value; those are here plotted at those values (e.g., for ≥ 320, the value is assumed to be 320). Some studies may report kinetics of different antibodies or using different assays (and different units) for the same patient. Note that while these are plotted on the same axes, values may not necessarily be comparable across studies within each panel, as each lab may have different assay conditions resulting in different scales. See Figures S2 and S3 for (more limited) data on SARS-CoV-1 and IgA.

MERS-CoV antibody kinetics.