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mRNA expression of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) in tuberous sclerosis complex (TSC) tubers. Quantitative real‐time PCR shows higher mRNA expression of MMP9, MMP14 (A) and TIMP4 (B) in cortical tubers from TSC patients compared to control tissue. mRNA expression of MMP2, MMP3, TIMP1, TIMP2, TIMP3 and TIMP4 did not change. *P < 0.05, **P < 0.01, ***P < 0.001; Mann–Whitney U‐Test.
