SNHG22 upregulation in PTC is related to poor clinical outcomes in patients.
(a) RT–qPCR analysis was used to evaluate SNHG22 expression in 65 pairs of PTC tissues and paired adjacent non-tumor tissues. RT-qPCR analysis was repeated at least thrice. * P < 0.05 vs. paired adjacent non-tumor tissues. (b) SNHG22 expression in five human PTC cell lines (K-1, HTH-7, HTH83, TPC-1, and BCPAP) and a nonmalignant thyroid cell line Nthy-ori3-1 was detected with RT–qPCR. RT-qPCR analysis was repeated at least thrice. *P < 0.05 vs. Nthy-ori3-1. (c) Kaplan–Meier survival curves revealed a relationship between SNHG22 expression and overall survival of patients with PTC. P = 0.035.