Table 2.
The correlation between miR-106a and Smad7 expression levels and the clinic pathological features of gastric cancer.
miR-106a |
Smad7 |
||||
---|---|---|---|---|---|
Characteristics | Number | Fold change ± SD | P-value | Fold change ± SD | P-value |
Sex | |||||
Male | 22 | 2.5118 ± 1.27580 | 0.135 | 0.7862 ± 1.02471 | 0.255 |
Female | 18 | 1.9917 ± 0.74372 | 0.4909 ± 0.38040 | ||
Age (years) | |||||
≥60 | 23 | 2.4683 ± 1.08208 | 0.202 | 0.6995 ± 0.98368 | 0.680 |
<60 | 17 | 2.0200 ± 1.07642 | 0.5910 ± 0.49821 | ||
Tumor site | |||||
Cardia | 7 | 2.4686 ± 1.20333 | 0.599 | 0.6204 ± 0.35941 | 0.971 |
Body | 5 | 2.6400 ± 1.00055 | 0.7324 ± 0.80316 | ||
Autumn | 28 | 2.1654 ± 1.09385 | 0.6474 ± 0.90220 | ||
Size (cm) | |||||
>5 | 9 | 3.3433 ± 1.05711 | 0.001# | 0.3257 ± 0.17514 | 0.014* |
3-5 | 26 | 2.0335 ± 0.94325 | 0.5908 ± 0.48357 | ||
≤3 | 5 | 1.6300 ± 0.55032 | 1.5693 ± 1.87072 | ||
Histology grade | |||||
Well | 5 | 1.1440 ± 0.33366 | 0.011* | 0.3842 ± 0.13025 | 0.432 |
Moderate + poor | 35 | 2.4397 ± 1.06374 | 0.6918 ± 0.85567 | ||
Lymph node | |||||
Yes | 24 | 2.6200 ± 1.20633 | 0.013* | 0.7118 ± 0.98777 | 0.580 |
No | 16 | 1.7644 ± 0.61991 | 0.5653 ± 0.42512 | ||
Serosal invasion | |||||
Yes | 27 | 2.5885 ± 1.13914 | 0.008# | 0.6977 ± 0.93522 | 0.621 |
No | 13 | 1.6323 ± 0.61242 | 0.5608 ± 0.45211 | ||
TNM stage | |||||
Ⅰ + Ⅱ | 9 | 1.5900 ± 1.00169 | 0.029* | 1.2937 ± 1.50424 | 0.005# |
Ⅲ + Ⅳ | 31 | 2.4774 ± 1.04471 | 0.4675 ± 0.28795 |
*P < 0.05, #P < 0.01.