Figure 2.

Up-regulated miR-129-5p restrains apoptosis of cells in the NP tissue of rats with IDD. (a) Apoptosis of cells in the NP tissues in each group of rats examined via TUNEL staining (the arrow indicated TUNEL staining positive cells); (b) Quantification results of (a); (c) Bax and Bcl-2 protein bands in the NP tissues of rats in each group; (d) Quantification results of (c). * vs the sham group, P < 0.05; & vs the agomir-NC group, P < 0.05; # vs the antagomir-NC group, P < 0.05. Ten rats in each group; the data were expressed as mean ± standard deviation. One-way ANOVA was used for data analysis, and pairwise comparison after ANOVA analysis was conducted via using Tukey’s post hoc test.