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Experiment flowchart (a), sequencing results of the region surrounding 241/242 (b) and expression levels of p53 in gene-edited and wild-type PFF cells (c). WT: wild-type; HO: homozygote; KO: knock out, 1, 2, 3, 4, 5 indicate 5 single clones with homozygous deletions. – - – -, base deletion. * P < 0.05.
