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. 2020 Apr 1;31(5):1107–1117. doi: 10.1681/ASN.2019121328

Table 2.

A clinical score to stratify risk of postnephrectomy eGFR <45 ml/min per 1.73 m2

Variable Coefficient Points Score Risk Stratum Predicted Probabilitya Observed Absolute Riskb Relative Risk (95% CI)c
Age, yr 0 Negligible 0.8% (0.2% to 1.6%) <2% 0.05 (0.00 to 0.35)
 <65 0.00 0 1
 ≥65 0.66 1 2
Diabetes mellitus 3
 No 0.00 0
 Yes 0.66 1 4 Low 6% (3% to 10%) 3%–14% 1.00
Preoperative eGFRd 5
 60–69 3.16 5 6
 70–79 2.41 4
 80–89 1.76 3 7 Moderate 23% (17% to 29%) 21%–26% 2.71 (1.51 to 4.91)
 ≥90 0.00 0 8
Management plan
 Partial nephrectomy 0.00 0 9 High 51% (43% to 59%) 46%–69% 5.93 (3.30 to 10.64)
 Radical nephrectomy 1.79 3 10

Logistic coefficients are from model 3 (Table 1). To derive the points system, each coefficient was divided by the lowest value (0.66) and rounded to the nearest integer. 95% CI, 95% confidence interval.

a

Mean (range) of predicted probability of the primary outcome for scores contained within respective strata.

b

Range of absolute risk of the outcome within each stratum across all four cohorts (excluding living kidney donor analysis).

c

Relative risk was calculated by comparing risk strata using a univariable log-binomial regression in the derivation cohort (with reference to the “low-risk” stratum).

d

eGFR in ml/min per 1.73 m2.