Table 1.

Expert position on the strengths and weaknesses of soluble urokinase plasminogen activator receptor (suPAR) for the prognosis of patients at the emergency department (ED)

Reference	Strengths
[10]	Concentrations > 6 ng/ml have high sensitivity for unfavourable outcome and signify considerable risk of death for patients admitted to the ED
[11]	Concentrations < 4 ng/ml have high NPV for unfavourable outcome and allow discharge of the patient from the ED
[14]	Concentrations < 12 ng/ml for patients with infections and systemic inflammatory response syndrome have high NPV for unfavourable outcome after 28 days

Reference	Limitations
[1]	Non-specific for certain disease entities
[3–6]	Comorbidities such as chronic renal disease, HIV infection, solid tumour malignancy increase baseline levels
[10]	Concentrations between 4 and 6 ng/ml do not clearly indicate the risk of unfavourable outcome for patients admitted to the ED

HIV human immunodeficiency virus, NPV negative predictive value