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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Chem Biol Interact. 2020 Mar 18;322:109056. doi: 10.1016/j.cbi.2020.109056

Figure 4.

Figure 4.

Thermodynamic box for complex substrate binding possibilities. The free energy for the conversion of E to E’S is identical for the conformational selection and induced fit routes [81].