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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Metab Eng. 2020 Mar 25;60:56–65. doi: 10.1016/j.ymben.2020.03.007

Fig. 4. Effects of manipulating target genes on growth and product formation in SA590-PK.

Fig. 4.

(A) Specific growth rate and (B) specific aldehyde productivity over 24 h (estimated from 6 to 30h time points in Fig. S5). Abbreviations indicate genes overexpressed in the control SA590-PK strain: ALS, acetolactate synthase (L. lactis); PK, pyruvate kinase (S. elongatus); αPDH, antisense RNA targeted to pyruvate dehydrogenase subunit B (S. elongatus); PCK, PEP carboxykinase (E. coli). Data ± SEM; n = 6 for SA590-PK, SA590-PK-αPDH, SA590-PK-PCK; n = 3 for SA590-PK-PK and SA590-PK-ALS. *p < 0.05 relative to control SA590-PK strain.