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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Addict Biol. 2019 Nov 13;25(6):e12842. doi: 10.1111/adb.12842

Fig.. 5.

Fig.. 5.

Effects of racemic α-PVP and its enantiomers on dose-effect functions for blood pressure (a) and heart rate (b). Rats were implanted with telemetry transmitters that sampled blood pressure and heart rate every 1 min for 3 hr. Data are expressed as mean ± SEM or sum (for activity counts) for n = 5–7 rats/group for the entire 3 hr sampling period. Solid symbols represent significant difference from respective saline (p < 0.05). The bottom panels present time-course for blood pressure (c) and heart rate (d) with the 1-min samples averaged over 10-min periods for the entire 3-hr session. Data are presented for saline sessions and the highest dose of each drug tested.