Fig. 3. CRP was negatively associated with prefrontal-limbic TSPO availability and positively associated with PTSD severity.
a Lower [11C]PBR28 VT was significantly associated with higher levels of CRP (R2 = 0.52, p = 0.005; β = −0.92, p = 0.029) in the PTSD group (n = 21). Displayed [11C]PBR28 VT values are adjusted for genotype and sex. b Higher CRP was significantly associated with greater PTSD severity (R2 = 0.21, p = 0.037) in the PTSD group (n = 21). Coefficient of determination and standardized coefficients were assessed using linear regression. Gray shading indicates 95% confidence intervals.