Table 1.
Participant characteristics and injection parameters.
| Characteristics | Control (n = 26) | PTSD (n = 23) | p-value |
|---|---|---|---|
| Age: years | 32 ± 12 | 38 ± 10 | 0.10 |
| Sex | 8 F, 18 M | 10 F, 13 M | 0.36 |
| Body mass index | 27.3 ± 4.3 | 27.8 ± 5.4 | 0.68 |
| rs6971 Genotype | 17 HAB, 9 MAB | 18 HAB, 5 MAB | 0.32 |
| Ethnicity (%) | 0.32 | ||
| African American | 6 (23) | 9 (39) | |
| Asian/Pacific Islander | 1 (4) | 1 (4) | |
| Caucasian | 12 (46) | 9 (39) | |
| Hispanic | 7 (27) | 4 (17) | |
| Clinical Characteristics | |||
| PTSD severity | |||
| CAPS-IV (n) | — | 71 ± 24 (10) | — |
| CAPS-5 (n) | — | 32 ± 10 (13) | — |
| Trauma exposure(s) | (n = 16) | ||
| Sexual trauma | 3 | 12 | — |
| Physical trauma | 10 | 21 | — |
| Childhood trauma | 11 | 23 | — |
| Combat | 3 | 9 | — |
| Accident/natural disaster | 13 | 17 | — |
| Years since primary trauma (n) | 16 ± 10 (12) | 16 ± 11 (22) | 0.91 |
| Current comorbid MDD | — | 18 | — |
| Currently on psychotropic medication | — | 5 | — |
| Current tobacco users | 12 | 8 | 0.41 |
| Current cannabis users | 4 | 7 | 0.21 |
| Current alcohol users | 17 | 13 | 0.53 |
| Injection parameters | |||
| Injected dose (MBq) | 502.6 ± 189.3 | 573.9 ± 165.7 | 0.17 |
| Injected mass (µg/kg)* | 0.03 ± 0.03 | 0.01 ± 0.01 | 0.022 |
| fP | 0.024 ± 0.008 | 0.020 ± 0.007 | 0.14 |
*significant at p < 0.05; assessed from two-sided independent samples t-test.
Values are Mean ± SD, unless otherwise specified.