Table 1.
Parameter | Immune phenotype | HGP | ||||
---|---|---|---|---|---|---|
Inflamed | Non-inflamed | P value | Angiogenic | Non-angiogenic | P value | |
Age (years) | 62.3 | 61.5 | 0.70 | 61.6 | 62.4 | 0.73 |
Sex | 0.38 | 0.82 | ||||
Male | 21 | 19 | 26 | 14 | ||
Female | 17 | 24 | 25 | 16 | ||
Radiological response | 0.39 | 0.018 | ||||
PR | 31 | 32 | 43 | 20 | ||
SD | 5 | 10 | 5 | 10 | ||
Histological response | 0.09 | 0.009 | ||||
MjHR | 19 | 11 | 25 | 5 | ||
PHR | 9 | 14 | 14 | 9 | ||
NHR | 10 | 17 | 12 | 15 | ||
Primary tumour side | 0.09 | 0.009 | ||||
Right | 14 | 8 | 19 | 3 | ||
Left | 24 | 34 | 31 | 27 | ||
Primary tumour site | 0.10 | 0.64 | ||||
Rectum | 10 | 19 | 17 | 12 | ||
Colon | 28 | 23 | 33 | 18 | ||
Number of metastases | 0.65 | 0.49 | ||||
1–2 | 24 | 24 | 32 | 16 | ||
>2 | 14 | 19 | 19 | 14 | ||
Size of metastases | 0.76 | 0.75 | ||||
≤5 cm | 33 | 36 | 44 | 25 | ||
>5 cm | 5 | 7 | 7 | 5 | ||
Timing of metastases | 1.00 | 0.24 | ||||
Metachronous | 13 | 15 | 15 | 13 | ||
Synchronous | 25 | 27 | 35 | 17 | ||
Distribution of metastases | 0.38 | 0.82 | ||||
Unilobar | 21 | 19 | 26 | 14 | ||
Bilobar | 17 | 24 | 25 | 16 | ||
KRAS status | 0.16 | 0.47 | ||||
mt | 10 | 19 | 16 | 13 | ||
wt | 25 | 23 | 31 | 17 | ||
Mismatch repair | 0.42 | 0.43 | ||||
Proficient | 29 | 41 | 60 | 45 | ||
Deficient | 1 | 0 | 0 | 1 |