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. 2020 May 12;10:144. doi: 10.1038/s41398-020-0825-7

Fig. 1. Discovery proteomic analysis of cerebrospinal fluid from psychiatric patients.

Fig. 1

a Hierarchical clustering analysis of differentially regulated proteins in CSF of psychiatric patients demonstrating a clear diverging of the psychiatric patients from the controls. b Volcano plot showing differentially regulated protein in CSF of MDD patients vs controls (in orange significant hits). For a and b, Student’s t test with permutation-based FDR (FDR 0.05, 250 randomizations). Shown are gene names. c Gene ontology enrichment analysis of differentially regulated proteins in the CSF of MDD patients. Fisher exact test (Benjamini–Hochberg FDR 0.05). GOBP gene ontology biological process.