Table 1.
Patient background and pre-anesthesia data
| Group N (N = 51) | Group L (N = 121) | P value | ||
|---|---|---|---|---|
| Age | years | 71 [64, 81] | 74 [66, 81] | 0.71 |
| Female | N (%) | 7 (14) | 38 (31) | 0.02* |
| Height | cm | 162 [158, 168] | 161 [155, 168] | 0.20 |
| Weight | kg | 60 [52, 69] | 59 [52, 69] | 0.85 |
| Body mass index | kg/m2 | 22.5 [20.2, 24.8] | 22.8 [20.8, 25.1] | 0.40 |
| ASA-PS (1/2/3) | N | 6/44/1 | 8/96/17 | |
| ASA-PS = 3 | N (%) | 1(2) | 17 (14) | 0.01* |
| TUR-Bt | N (%) | 42 (82) | 64 (53) | < 0.001* |
| Preoperative condition | ||||
| Heart disease | N (%) | 1 (2) | 20 (17) | 0.009* |
| Atrial fibrillation or PAf | N (%) | 1 (2) | 13 (11) | 0.07 |
| Other disease | N (%) | 0 (0) | 12 (10) | 0.02* |
| Diabetes mellitus | N (%) | 7 (14) | 19 (16) | 0.82 |
| Liver dysfunction | N (%) | 3 (6) | 7 (6) | 1.00 |
| eGFR | ml/m2 | 73 [57, 84] | 69 [57, 82] | 0.64 |
| Hypertension | N (%) | 26 (51) | 66 (55) | 0.74 |
| Use of calcium blocker | N (%) | 21 (41) | 52 (43) | 0.87 |
| Use of RAS inhibitor | N (%) | 15 (29) | 38 (31) | 0.86 |
| Use of psychiatric drugs | N (%) | 1 (2) | 5 (4) | 0.67 |
| Preoperative hematocrit | % | 39.6 [37.7, 42.8] | 38.5 [35.9, 42.0] | 0.06 |
| Pre ALA systolic BP | mmHg | 128 [117, 143] | 124 [114, 138] | 0.17 |
| Pre ALA mean BP | mmHg | 92 [84, 101] | 91 [84, 97] | 0.41 |
| Pre ALA heart rate | beats/min | 65 [60, 74] | 66 [60, 72] | 0.98 |
| ALA to anesthesia induction | min | 167 [140, 202] | 158 [142, 187] | 0.51 |
| Systolic BP before induction | mmHg | 130 [117, 150] | 122 [109, 136] | 0.01* |
| Mean BP before induction | mmHg | 92 [84, 102] | 90 [84, 97] | 0.41 |
| Difference systolic BP | mmHg | 4 [-7, 16] | -2 [-15, 11] | 0.13 |
| Difference mean BP | mmHg | 2 [-4, 11] | -10 [-3, 7] | 0.01* |
| Heart rate before induction | beats/min | 65 [60, 74] | 66 [60, 72] | 0.98 |
| General anesthesia | N (%) | 13 (25) | 107 (88) | <0.001* |
N number, ASA-PS American Society of Anesthesiologists physical status classification, TUR-Bt transurethral resection of the bladder tumor, PAf paroxysmal Af, eGFR estimated glomerular filtration rate, RAS renin-angiotensin system, ALA 5-aminolevulinic acid, BP blood pressure, Pre ALA before 5-ALA intake, ALA to anesthesia induction time from 5-ALA intake to anesthesia induction, before induction before anesthesia induction, Difference difference in BP before 5-ALA intake and before anesthesia induction ([BP anesthesia induction]−[BP before5-ALA intake])
*p < 0.05