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. 2020 May 6;7:178. doi: 10.3389/fmed.2020.00178

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Copyright © 2020 Xiang, Cao, Shen, Chen, Guo, Ding and Zou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of DDR protein in T cells by IS intervention. Protein level of p-ATM, p-ATR, p-p53 and p-BRCA1 were significantly higher in IS 500 μM group compared with the control group. Protein level of p-BRCA1 were also increased in IS 200 μM group. AhR were also up-regulated in IS 200 μM and IS 500 μM group. *P < 0.05 compared with the control group.