Table 2.
Subgroup analysis and sensitivity analyses on primary outcome.
| Subgroup | No. of studies | No. of patients | RR (95% CI) | I2 | P value | |
|---|---|---|---|---|---|---|
| Intervention | ||||||
| Vasopressin | 10 | 2,147 | 0.96 (0.87–1.06) | 0% | 0.44 | |
| Analogs | 13 | 2,093 | 0.91 (0.82–1.01) | 3% | 0.07 | |
| Clinical setting | ||||||
| Septic shock only | 16 | 3,487 | 0.94 (0.87–1.03) | 0% | 0.20 | |
| Septic shock with complications | 7 | 738 | 0.91 (0.80–1.03) | 40% | 0.15 | |
| Outcome measurement | ||||||
| 28-day or 30-day mortality | 17 | 4,022 | 0.95 (0.88–1.02) | 0% | 0.18 | |
| ICU mortality | 4 | 151 | 0.82 (0.63–1.07) | 2% | 0.15 | |
| Risk of bias | ||||||
| Low risk | 16 | 3,637 | 0.95 (0.88–1.03) | 0% | 0.22 | |
| High risk | 7 | 588 | 0.87 (0.74–1.02) | 29% | 0.09 | |
| Publication type | ||||||
| Full text | 17 | 3,191 | 0.95 (0.87–1.04) | 0% | 0.30 | |
| Abstract | 6 | 1,034 | 0.90 (0.79–1.02) | 55% | 0.09 | |
ICU, intensive care unit; RR, risk ratio; CI, confidence interval.