Table 6.
Gene set enrichment analysis of AD modules.
ID | # Gene | # AD egene | P-value | FDR | GSEA inferred module function | AD-relevant evidence |
---|---|---|---|---|---|---|
AD1 | 88 | 6 | 6.36E-09 | 5.09E-08 | Immune response | Wang et al., 2018 |
AD2 | 42 | 3 | 5.16E-05 | 2.07E-04 | WNT signaling pathway, Dopaminergic neuron differentiation | dos Santos and Smidt, 2011 |
AD3 | 177 | 4 | 2.28E-04 | 6.08E-04 | Immune response, JAK/STAT signaling pathway | Nicolas et al., 2013 |
AD4 | 52 | 2 | 3.73E-03 | 7.47E-03 | ER/Golgi trafficking, Glycosaminoglycans metabolism | Placido et al., 2014 |