Table 3.
Summary of adverse events related to RMD1−2−3 treatment (n = 15).
| Grade 1 n | Grade 2 n | Grade 3 n | Grade 4 n | Total n (%) | |
|---|---|---|---|---|---|
| Headache | 9 | 5 | 0 | 0 | 14 (93) |
| Fatigue | 9 | 5 | 0 | 0 | 14 (93) |
| Nausea | 4 | 7 | 0 | 0 | 11 (73) |
| Anorexia | 8 | 1 | 0 | 0 | 9 (60) |
| Abdominal pain | 5 | 2 | 0 | 0 | 7 (47) |
| Metallic taste | 5 | 1 | 0 | 0 | 6 (40) |
| Constipation | 4 | 2 | 0 | 0 | 6 (40) |
| Abdominal distension | 4 | 1 | 0 | 0 | 5 (33) |
| Vomits | 4 | 0 | 0 | 0 | 4 (27) |
| Sweating | 2 | 2 | 0 | 0 | 4 (27) |
| Palpitations | 3 | 0 | 0 | 0 | 3 (20) |
| Myalgia | 1 | 1 | 0 | 0 | 2 (13) |
| Rash | 0 | 2 | 0 | 0 | 2 (13) |
| Dry mouth | 1 | 0 | 0 | 0 | 1 (7) |
| ECG: ST-elevation | 1 | 0 | 0 | 0 | 1 (7) |
| Anxiety | 0 | 1 | 0 | 0 | 1 (7) |
| Libido decrease | 0 | 1 | 0 | 0 | 1 (7) |
| Somnolence | 1 | 0 | 0 | 0 | 1 (7) |
| Sepsis by Shigella sonnei (SAE) | 0 | 0 | 0 | 1 | 1 (7) |
| Hypotension | 0 | 1 | 0 | 0 | 1 (7) |