TABLE 2.
Serum and urine biomarkers of 19 non-elite marathon runners.
| Parameters (normal reference values) | 24 h pre-race (1) | Immediately post-race (2) | 48 h post-race (3) | F P valuea | SE P value1-2b | SE P value1-3b | SE P value2-3b |
| Serum Creatinine (mg/dL) (0.6–1.2 mg/dL) | 0.96 ± 0.09 | 1.28 ± 0.20 | 0.91 ± 0.09 | 46.491 0.000 |
0.039 0.000 |
0.013 0.014 |
0.038 0.000 |
| Serum Urea (mg/dL) (17–43 mg/dL) | 35.2 ± 8.9 | 43.2 ± 9.4 | 35.2 ± 6.9 | 10.326 0.001 |
1.919 0.002 |
1.496 1.000 |
1.851 0.001 |
| Serum Sodium (mmol/L) (135–145 mmol/L) | 139.3 ± 1.1 | 141.6 ± 3.0 | 139.2 ± 1.5 | 6.214 0.009 |
0.720 0.010 |
0.449 1.000 |
0.716 0.007 |
| Serum Osmolality (mmol/kg) (285–295 mmol/kg) | 287.0 ± 3.9 | 292.7 ± 6.6 | 285.2 ± 2.2 | 14.109 0.000 |
1.488 0.001 |
1.488 0.663 |
1.488 0.000 |
| Parameters (normal reference values) | 24 h pre-race (1) | Immediately post-race (2) | 48 h post-race (3) | Chi-square P valuec | Z P value2-1d | Z P value3-1d | Z P value3-2d |
| Serum CRP (mg/L) (0–5.0 mg/L) | 0.70 (0.20–5.30) |
0.50 (0.20–3.00) |
7.50 (3.20–15.50) |
30.778 0.000 |
−1.880 0.050 |
−3.824 0.000 |
−3.825 0.000 |
| Serum CK (U/L) (20–215 U/L) | 140 (76–400) | 376 (260–946) | 685 (194–1882) | 31.684 0.000 |
−3.823 0.000 |
−3.823 0.000 |
−3.099 0.000 |
| Hematuria | 0 | 1 case | 0 | – | – | – | – |
| Proteinuria | 0 | 5 cases | 0 | – | – | – | – |
aRepeated measures ANOVA test; bBonferroni test; cFriedman test with Chi-square; dWilcoxon test. CRP, C-reactive protein; CK, creatine kinase.