Table 2.

Study Design for Evaluating AAVhu68 Administration via Lumbar Puncture to NHPs of Different Ages Using a Clinically Relevant Injection Volume

Age (years)	Route of Administration	Number of Animals
3	ICM	3
1	LP	4
1.5	LP	4
2	LP	3
3	LP	3

NHPs were administered 1.5 × 10¹³ GC of an AAVhu68 vector expressing a GFP transgene at a dose of 0.7 mL. The study duration was 21 days.