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. 2020 Apr 21;20:711–724. doi: 10.1016/j.omtn.2020.04.006

Figure 3.

Figure 3

ROC Curve Analysis of Each Validated miRNA for Evaluation of Biomarker Potential

(A–F) ROC curve evaluated (A) miR-133b in LCa tissues compared to the paired normal counterparts (sensitivity = 0.80, specificity = 0.64, AUC = 0.76); (B) miR-652 in LCa tissues compared to the paired normal counterparts (sensitivity = 0.61, specificity = 0.56, AUC = 0.54); (C) miR-449a in LCa tissues compares to the paired normal counterparts (sensitivity = 0.68, specificity = 0.54, AUC = 0.59); (D) miR-133b in N+ compared to N− (sensitivity = 0.56, specificity = 0.63, AUC = 0.56); (E) miR-652 in N+ compared to N− (sensitivity = 0.78, specificity = 0.47, AUC = 0.55); and (F) miR-449a in N+ compared to N− (sensitivity = 0.55, specificity = 0.76, AUC = 0.67).