Figure 5.

miR-449a Suppresses Cell Migration and Invasion in LCa Cells

(A) Cell migration was assessed by a wound-healing assay in Hep-2 transfected with miR-449a mimic or inhibitor, or the corresponding NC. (B) Cell invasion was evaluated in Hep-2 transfected with miR-449a mimic or inhibitor, or the corresponding NC employing a transwell invasion assay. The purple region indicates invaded cells, and black dots show pores of transwell chamber. Each sample was run in triplicate. Error bars show mean ± SD. The t test was used for the calculation of p values. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.