Table 2.

Significantly Deregulated miRNAs among Laryngeal Cancer Tissues Compared to Their Paired Noncancerous Counterparts

MicroRNA	ΔΔCt	2−ΔΔCt (FC)	95% CI for FC	Regulation	p Value	FDR-Adjusted p Value
miR-133b	3.55	0.08	−0.07–2.69	down	0.0004	0.06
miR-184	−3.61	12.1	5.44–41.87	up	0.0004	0.06
miR-181a	−2.14	4.29	2.70–6.59	up	0.0016	0.17
miR-1	3.46	0.09	−0.03–1.47	down	0.0029	0.23
miR-140-3p	1.30	0.41	0.32–0.62	down	0.0060	0.34
miR-198	−3.76	13.9	−0.95–36.12	up	0.0069	0.34
miR-885-5p	4.06	0.06	0.05–0.55	down	0.0087	0.35
miR-139-5p	1.79	0.29	0.22–0.44	down	0.0124	0.35
miR-590-5p	−1.18	2.30	1.47–2.52	up	0.0126	0.35
miR-324-3p	−0.86	1.87	0.98–2.02	up	0.0138	0.35
miR-886-3p	−1.81	3.48	0.84–6.82	up	0.0145	0.35
miR-196b	−2.91	7.46	5.93–15.58	up	0.0166	0.35
miR-449b	1.60	0.33	0.10–2.31	down	0.0170	0.35
miR-185	−2.34	4.92	2.85–7.06	up	0.0174	0.35
miR-155	−1.10	2.14	1.58–2.93	up	0.0180	0.35
miR-28	−1.49	2.83	1.82–3.56	up	0.0192	0.35
miR-142-3p	−2.23	4.59	3.59–5.53	up	0.0194	0.35
miR-490	−1.56	3.03	1.46–4.37	up	0.0216	0.35
miR-331-5p	−4.40	21.1	6.02–32.57	up	0.0241	0.35
miR-20b	−0.90	2.00	1.26–2.23	up	0.0244	0.35
miR-21	−2.90	8.00	5.16–11.52	up	0.0248	0.35
miR-425-5p	−1.31	2.46	1.73–4.56	up	0.0250	0.35
miR-147b	−1.81	3.48	1.67–7.65	up	0.0256	0.35
miR-133a	5.17	0.03	−0.07–0.96	down	0.0265	0.35
miR-301	−2.71	6.50	4.96–10.23	up	0.0312	0.39
miR-539	1.73	0.31	−0.24–2.89	down	0.0337	0.41
miR-375	3.92	0.07	0.11–0.49	down	0.0367	0.42
miR-132	−1.01	2.00	1.54–2.55	up	0.0380	0.42
miR-138	−1.75	3.25	2.05–6.96	up	0.0381	0.42
miR-182	−1.88	3.73	2.42–5.10	up	0.0396	0.42

The t test was used for the calculation of p values. The 95% CI was calculated from fold change of each miRNA level.